Socio-demographic Factors Affecting Health-related-quality of Life in Post-renal-transplant Patients
Abstract
Objective: The objective of this study was to identify the socio-demographic factors affecting health related quality of life in renal transplant recipients.
Material and Methods: A census of all registered post-renal-transplant patients was conducted from October 1, 2018, to January 31, 2019. Data were collected on a Kidney Disease Quality of Life questionnaire (SF-1.3) and analysed by Statistical Package for the Social Science (SPSS). Scores in the three main domains, physical component summary (PCS), mental component summary (MCS), and kidney disease component summary, were calculated. Mean scores for gender, type of donor, and employment were compared by unpaired t-test, while mean scores for age, level of education, and duration of transplant were compared by analysis of variance.
Results: Out of 315 patients, 277 (87.9%) were males and 38 (12.1%) were females. The mean age was 37.26 (±10.14) years. Live unrelated transplants were 58.41% while live related transplants were 41.58%. Males had a significantly higher average (p-value=0.001) PCS score, but females had significantly higher average (p-value=0.05) MCS score. There was variation with respect to the PCS (p-value=0.031) and MCS (p-value=0.001) scores in the different age categories. The education groups varied significantly with respect to MCS (p-value=0.05). The recipients of live unrelated transplants had significantly lower average PCS score.
Conclusion: The female gender, live related donor and variations in ages were associated with lower PCS scores, while male gender, variations in ages, and education were associated with lower MCS scores. This study demonstrates that the Kidney Disease Quality of Life Short Form-1.3 (KDQOL SF-1.3) is a good tool to reveal differences in HRQOL scores in renal transplant recipients.
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Ramakrishnan K, Bond TC, Claxton A, Sood VC, Kootsikas M, Agnese W, et al. Clinical characteristics and outcomes of end-stage renal disease patients with self-reported pruritus symptoms. Int J Nephrol Renovasc Dis 2013;7:1-12.
Lin X-J, Lin IM, Fan S-Y. Methodological issues in measuring health-related quality of life. Tzu Chi Med J 2013;25:8-12.
Jessani S, Bux R, Jafar TH. Prevalence, determinants, and management of chronic kidney disease in Karachi, Pakistan-a community based cross-sectional study. BMC Nephrol 2014; 15:90.
Rizvi SAH, Anwar Naqvi SA, Zafar MN, Hussain Z, Hashmi A, Akhtar F, et al. Pakistan abolishes kidney market and ushers in a new era of ethical transplantation. Int J Organ Transplant Med 2010;1:193-7.
Jha V. Current status of end-stage renal disease care in India and Pakistan. Kidney Int Suppl 2013;3:157-60.
Chan-On C, Sarwal MM. A comprehensive analysis of the current status and unmet needs in kidney transplantation in Southeast Asia. Front Med 2017;4:84.
Rizvi SA, Naqvi SA, Hussain Z, Hashmi A, Akhtar F, Hussain M, et al. Renal transplantation in developing countries. Kidney Int Supple 2003;83:96-100.
Muehrer RJ, Becker BN. Life after transplantation: new transitions in quality of life and psychological distress. Semin Dial 2005;18:124-31.
Bansal A. Quality of life in kidney transplant patients: an exploration of instruments, group comparisons, correlates, and outcomes. JULS 2016;10:62-5.
Molnar-Varga M, Molnar MZ, Szeifert L, AZ K, Kelemen A, Becze A, et al. Health-related quality of life and clinical outcomes in kidney transplant recipients. Am J Kidney Dis 2011;58:444-52.
Bohlke M, Marini SS, Rocha M, Terhorst L, Gomes R, Barcellos FC, et al. Factors associated with health-related quality of life after successful kidney transplantation: a population-based study. Qual Life Res 2009;18:1185-93.
Mendonça AEO, Torres GV, Salvetti MG, Alchieri JC, Costa, IK. Changes in quality of life after kidney transplantation and related factors. Acta Paulista de Enfermagem 2014;27:287-92.
Anees M, lbrahim M, Imtiaz M, Batool S, Elahi I, Malik MR. Translation, validation and reliability of the Kidney Diseases Quality of Life-Short Form (KDQOL-SF Form) Tool in Urdu. JCPSP 2016;26:651-4.
Moller PH, Smith R, Petr P. The SF-36 Questionnaire: a tool to assess health-related quality of life [homepage on the Internet]. Ceske Budejovice: University of South Bohemia in Ceske Budejovice; 2000 [cited 2020 Jun 4]. Available from: http:// www.zsf.jcu.cz/structure/departments/kvz/…/12DotaznikSF36. doc/Google Scholar
Alvares J, Cesar C, Acurcio F, Andrade E, Cherchiglia M. Quality of life of patients in renal replacement therapy in Brazil: comparison of treatment modalities. Qual Life Res 2012; 21:983- 91.
Mersal FA, Aly RAES. Effect of patient education on coping, quality of life,knowledge and self efficacy of kidney recipient patients. Am J Nurs Sci 2014;3:78-86.
Gautam R, Balwani M, Kute V, Godhani U, Ghule P, Shah P, et al. Health-related quality of life in postrenal transplant patients: a single-center study. Indian J Transplant 2018;12:35-40.
Taghizadeh-Afshari A, Ghareh-Aghagia SR, Kazeminejad A. The survey of kidney transplantation effect on hemodialysis patient’s quality of life in Uromieh. Uromieh Med J 2006;17:175- 80.
Lønning K, Heldal K, Bernklev T, Brunborg C, Andersen MH, von der Lippe N, et al. Improved health-related quality of life in older kidney recipients 1 year after transplantation. Transplant Direct 2018;4:e351.
Jha V, Garcia-Garcia G, Iseki K, Li Z, Naicker S, Plattner B, et al. Chronic kidney disease: global dimension and perspectives. Lancet 2013;382:260-72.
Matas AJ, Gillingham KJ, Humar A, Kandaswamy R, Sutherland DE, Payne W, et al. Kidney transplant recipients with 10 years of graft function: what happens next?. Am J Transplant 2008;8:2410-9.
Van der Mei SF, Kuiper D, Groothoff JW, van den Heuvel WJA, van Son WJ, Brouwer S. Long-term health and work outcomes of renal transplantation and patterns of work status during the end-stage renal disease trajectory. J Occup Rehabil 2011;21:325-34.
Alvares J, Cesar C, Acurcio F, Andrade E, Cherchiglia M. Quality of life of patients in renal replacement therapy in Brazil, Comparison of treatment modalities. Qual Life Res 2012;21: 983-1.
Neipp M, Karavul B, Jackobs S, zu Vilsendorf AM, Richter N, Becker T, et al. Quality of life in adult transplant recipients more than 15 years after kidney transplantation. Transplantation 2006;81:1640-4.
Danuser B, Simcox A, Studer R, Koller M, Wild P. Psychosocial Interest Group STCS. Employment 12 months after kidney transplantation: an in-depth bio-psycho-social analysis of the Swiss Transplant Cohort. Plos One 2017;12:e0175161.
Dobbels F, De Bleser L, De Geest S, Fine R. Quality of life after kidney transplantation: the bright side of life? Adv Chronic Kidney Dis 2007;14:370-8.
Kong IL, Molassiotis A. Quality of life, coping and concerns in Chinese patients after renal transplantation. Int J Nurs Stud 1999;36:313-22.
Antunes AVSL, Justo C, Ferrer J, Frade F, Severino SSP, Santos MJA. Assessment of the perceived quality of life of a kidney transplant patient. Enferm Nefrol 2018;21:138-44.
Sajjad I, Baines L, Patel P, Salifu MO, Jindal RM. Commercialization of kidney transplants: a systematic review of outcomes in recipients and donors. Am J Nephrol 2008;28:744-54.
Ivanovski N, Masin J, Rambabova-Busljetic I, Pusevski V, Dohcev S, Ivanovski O, et al. The outcome of commercial kidney transplant tourism in Pakistan. Clinic Transplant 2011;25:171-3.
Wei TY, Chiang YJ, Hsieh CY, Weng LC, Lin SC, Lin MH. Health related quality of life of long-term kidney transplantation recipients. Biomed J 2013;36:243-51.
Goetzmann L, Ruegg L, Stamm M, Ambühl P, Boehler A, Halter J, et al. Psychosocial profiles after transplantation: a 24-month follow-up of heart, lung, liver, kidney and allogeneic bone-marrow patients. Transplantation 2008;86:662-8.
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