Efficacy of Silver Diamine Fluoride for Arresting Non-cavitated Lesions on Approximal Surfaces in Permanent Teeth
Abstract
Objective: To evaluate the efficacy of silver diamine fluoride for arresting non-cavitated lesions on approximal surfaces in permanent teeth.
Material and Methods: This randomized controlled trial included 82 participants (396 lesions), aged 6−18 years that had at least one non-cavitated carious lesion on approximal surfaces. They were randomly allocated to either the SDF or sodium fluoride (NaF) group. After tooth separation at baseline (T0), the allocated intervention was applied directly on non-cavitated lesions. Clinical and radiographic examinations were performed to assess caries status at T0 and 6 months (T6).
Results: After 6 months, 77 participants (379 lesions) remained in this study. The caries arrest rates of the SDF group were significantly higher than those in the NaF group. From clinical examination, the proportions of caries arrest rate of the SDF and NaF groups were 100.0% and 80.1%, respectively. These high caries arrest rates were consistently demonstrated from radiographic examination in the SDF and NaF groups at 98.4% and 93.5%, respectively.
Conclusion: At the 6-month follow-up, 38.0% SDF was more effective than 5.0% NaF in arresting non-cavitated carious lesions on approximal surfaces in permanent teeth, and SDF could be a potential treatment option for minimally invasive caries management.
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