Age, Sex, Population Density and COVID-19 Pandemic in Thailand: A Nationwide Descriptive Correlational Study
Abstract
Objective: It is reported that age and sex have been identified as potential risk factors for severe outcomes and the distribution of coronavirus disease (COVID-19), although the specifics of these relationships are unclear. Furthermore, little is known about the relationship between age, sex, COVID-19, and population density in Thailand. This study proposed to examine the relationships among age, sex, population density, and the number of COVID-19 patients in Thailand.
Material and Methods: In this nationwide descriptive correlational study, the dataset of daily COVID-19 cases in Thailand between January 12, 2020, and November 30, 2020, and population density (people/km2 ) in each province of Thailand was retrieved from the Open Government Data of Thailand, the Registration Office Department of the Interior, the Ministry of the Interior, and the National Statistical Office of Thailand. Chi-square and Pearson product-moment correlation were used to determine the difference and relationships among studied variables. Simple linear regression was used to predict the number of COVID-19 cases based on population density.
Results: The findings illustrated a significant difference between male and female patients, in which the number of male patients was higher than female patients across age groups 31-45 years, 40-60 years, and >60 years (p-value<0.010). Further, population density was significantly associated with the number of COVID-19 cases.
Conclusion: This investigation would provide intervention planning implications during potential future pandemics, especially in groups at higher risk (males, age 17-46 years old, and people living in high-density population areas).
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Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. lancet 2020;395:497-506.
Guan W-j, Ni Z-y, Hu Y, Liang W-h, Ou C-q, He J-x, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020;382:1708-20.
COVID-19 CORONAVIRUS PANDEMIC Worldometer. [homepage on the Internet]. Worldometers; 2020 [cited 2021 Mar 17]. Available from: https://www.worldometers.info/ coronavirus/?
Srichannil C. The COVID-19 pandemic and Thailand: A psychologist’s viewpoint. Psychol Trauma 2020;12:485.
Boehmer TK, DeVies J, Caruso E, van Santen KL, Tang S, Black CL, et al. Changing age distribution of the COVID-19 pandemic—United States, May–August 2020. MMWR Morb Mortal Wkly Rep 2020;69:1404.
COVID TC, Team R. Severe outcomes among patients with Coronavirus Disease 2019 (COVID-19)-United States, February 12-March 16, 2020. MMWR Morb Mortal Wkly Rep 2020;69: 343-6.
Klein SL, Dhakal S, Ursin RL, Deshpande S, Sandberg K, Mauvais-Jarvis F. Biological sex impacts COVID-19 outcomes. PLoS pathog 2020;16:e1008570.
Kragholm K, Andersen MP, Gerds TA, Butt JH, Østergaard L, Polcwiartek C, et al. Association between male sex and outcomes of Coronavirus Disease 2019 (Covid-19)–a Danish nationwide, register-based study. Clin Infect Dis 2020. doi: 10.1093/cid/ciaa924.
Rashed EA, Kodera S, Gomez-Tames J, Hirata A. Influence of absolute humidity, temperature and population density on COVID-19 spread and decay durations: multi-prefecture study in Japan. Int J Environ Res Public Health 2020;17:5354.
Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 2020; 395:1054-62.
Karthik L, Kumar G, Keswani T, Bhattacharyya A, Chandar SS, Rao KB. Protease inhibitors from marine actinobacteria as a potential source for antimalarial compound. PloS One 2014; 9:e90972.
Grasselli G, Zangrillo A, Zanella A, Antonelli M, Cabrini L, Castelli A. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region, Italy. JAMA 2020;323;1574-81.
Klein S, Pekosz A, Passaretti C, Anker M, Olukoya P. Sex, gender and influenza. Geneva: WHO; 2010;p1-58.
Karlberg J, Chong D, Lai W. Do men have a higher case fatality rate of severe acute respiratory syndrome than women do? Am J Epidemiol 2004;159:229-31.
Matsuyama R, Nishiura H, Kutsuna S, Hayakawa K, Ohmagari N. Clinical determinants of the severity of Middle East respiratory syndrome (MERS): a systematic review and metaanalysis. BMC Public Health 2016;16:1-10.
Ahmed SB, Dumanski SM. Sex, gender and COVID-19: a call to action. Can J Public Health 2020;111:980-3.
Channappanavar R, Fett C, Mack M, Ten Eyck PP, Meyerholz DK, Perlman S. Sex-based differences in susceptibility to severe acute respiratory syndrome coronavirus infection. J Immunol 2017;198:4046-53.
Liu J, Ji H, Zheng W, Wu X, Zhu JJ, Arnold AP, et al. Sex differences in renal angiotensin converting enzyme 2(ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent. Biol Sex Differ 2010;1:6.
South AM, Diz DI, Chappell MC. COVID-19, ACE2, and the cardiovascular consequences. Am J Physiol Heart Circ Physiol 2020;318:H1084-90.
Hamel L, Salganicoff A. Is there a widening gender gap in coronavirus stress? [homepage on the Internet]. San Francisco, CA: Kaiser Family Foundation; 2020 [cited 2021 Mar 17]. Available from: https://www.kff.org/policywatch/is-there-widening-gender-gap-in 308 coronavirusstress/
Thompson AE, Anisimowicz Y, Miedema B, Hogg W, Wodchis WP, Aubrey-Bassler K. The influence of gender and other patient characteristics on health care-seeking behaviour: a QUALICOPC study. BMC Fam Pract 2016;17: 38.
Cai H. Sex difference and smoking predisposition in patients with COVID-19. Lancet Respir Med 2020;8:e20.
Conti P, Younes A. Coronavirus COV-19/SARS-CoV-2 affects women less than men: clinical response to viral infection. J Biol Regul Homeost Agents 2020;34:339-43.
Ahmad S. Potential of age distribution profiles for the prediction of COVID-19 infection origin in a patient group. Inform Med Unlocked 2020;20:100364.
Zheng Z, Peng F, Xu B, Zhao J, Liu H, Peng J, et al. Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis. J Infect 2020;81:e16-25.
Nagata JM. Supporting Young Adults to Rise to the Challenge of COVID-19. J Adolesc Health 2020;67:297-8.
Allam Z. The second 50 days: a detailed chronological timeline and extensive review of literature documenting the COVID-19 pandemic from day 50 to day 100. In: Allam Z, editor. Surveying the Covid-19 pandemic and its implications. Geelong Victoria: Elsevier; 2020;p.9-39.
Sarkar A, Liu G, Jin Y, Xie Z, Zheng Z. Public health preparedness and responses to the COVID-19 pandemic in South Asia: A situation and policy analysis. Glob Health J 2020;4:121-32.
International Tourist Arrivals to Thailand 2020 Ministry of Tourism & Sport 2020 [homepage on the Internet]. Bangkok: Ministry of Tourism and Sports; 2020 [cited 2020 Dec 17]. Available from: https://www.mots.go.th/
Bhadra A, Mukherjee A, Sarkar K. Impact of population density on Covid-19 infected and mortality rate in India. Model Earth Syst Environ 2020. doi: 10.1007/s40808-020-00984-7.
Qian M, Jiang J. COVID-19 and social distancing. Z Gesundh Wiss 2020. doi: 10.1007/s10389-020-01321-z.
VoPham T, Weaver MD, Hart JE, Ton M, White E, Newcomb PA. Effect of social distancing on COVID-19 incidence and mortality in the US. Med Rxiv 2020. doi: 10.1101/2020.06.10. 20127589.
Sy KTL, White LF, Nichols BE. Population density and basic reproductive number of COVID-19 across United States counties. Med Rxiv 2020. doi: 10.1101/2020.06.12.20130021.
Mecenas P, Bastos R, Vallinoto A, Normando D. Effects of temperature and humidity on the spread of COVID-19: A systematic review. Plos One 2020. doi:org/10.1371/journal. pone.0238339.
Auler A, Cássaro F, da Silva V, Pires L. Evidence that high temperatures and intermediate relative humidity might favor the spread of COVID-19 in tropical climate: A case study for the most affected Brazilian cities. Sci Total Environ 2020: 729:139090.
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